产品货号：
Z15842
中文名称：
DISC1抗体
英文名称：
Anti-DISC1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DISC1 Antibody |
| 指标别名 | C1orf136;DISC1;DISC1 long;disrupted in schizophrenia 1;KIAA0457;SCZD9 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | DISC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | DISC1 antibody was raised against an 18 amino acid synthetic peptide from near the center of human DISC1.The immunogen is located within amino acids 350 - 400 of DISC1. |
| 计算分子量 | 94kDa |
| 成分 | DISC1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | DISC1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Disrupted in schizophrenia 1 (DISC1) is a candidate gene for susceptibility to schizophrenia.It was discovered through chromosomal analysis of a large Scottish family whose members exhibited schizophrenia and related psychiatric disorders.Through yeast two-hybrid screening,it was discovered that DISC1 interacts with many members of the centrosome and cytoskeletal system including MAP1A and Nudel.More recently,DISC1 has been found to regulate the transport of a complex containing Nudel,the lissencephaly-1 (LIS1) protein,and 14-3-3epsilon from neuronal cell bodies to the axons by the action of the microtubule-dependent directed motor protein kinesin-1,also known as KIF5A.Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration,resulting in aberrant morphological development,suggesting that DISC1 plays a role in dendritic development and synapse formation. |
| Uniprot ID | Q9NRI5 |
| 基因名全称 | Disrupted in schizophrenia 1 |
| 蛋白名全称 | Disrupted in schizophrenia 1 |
| 推荐稀释比 | DISC1 antibody can be used for detection of DISC1 by Western blot at 0.5 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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